Allergy & Immunology

The Division of Allergy and Immunology offers a broad range of diagnostic and treatment options in allergies and immunologic diseases.

An allergy is an exaggerated immune response [1] or reaction to substances that are generally not harmful.

See also:

• Allergic conjunctivitis
• Allergic reactions [2]
• Allergy testing [3]
• Allergy to mold, dander, dust [4]
• Atopic dermatitis [5] (eczema)
• Contact dermatitis
• Drug allergies
• Food allergies [6]
• Hay fever [7] (allergic rhinitis)

Causes

Allergies are relatively common. Both genetics and environmental factors play a role.

The immune system normally protects the body against harmful substances, such as bacteria and viruses. It also reacts to foreign substances called allergens, which are generally harmless and in most people do not cause a problem.

But in a person with allergies, the immune response is oversensitive. When it recognizes an allergen, it releases chemicals such as histamines. which fight off the allergen. This causes itching, swelling, mucus production, muscle spasms, hives [8],rashes [9], and other symptoms, which vary from person to person.

Common allergens include pollen, mold, pet dander, and dust. Food and drug allergies are common. Allergic reactions can also be caused by insect bites [10], jewelry, cosmetics, spices, and other substances.

Some people have allergy-like reactions to hot or cold temperatures, sunlight, or other environmental triggers. Sometimes, friction (rubbing or roughly stroking the skin) will cause symptoms.

A specific allergy is not usually passed down through families (inherited). However, if both your parents have allergies, you are likely to have allergies. The chance is greater if your mother has allergies.

Allergies may make certain medical conditions such as sinus problems, eczema [5], and asthma worse.

Symptoms

Allergy symptoms vary, but may include:

• Breathing problems (coughing, shortness of breath)
• Burning, tearing, or itchy eyes
• Conjunctivitis [11] (red, swollen eyes)
• Coughing
• Diarrhea
• Headache
• Hives
• Itching of the nose, mouth, throat, skin, or any other area
• Runny nose
• Skin rashes
• Stomach cramps
• Vomiting
• Wheezing